(Seattle, WA) -- Tim Beckham and Domingo Santana each hit a pair of home runs to lead the Mariners to a 12-4 demolition of the Red Sox in their home opener. The Mariners chased Chris Sale after three innings. Seattle improves to 3-and-0 to begin the season. The Mariners will take on Boston in the second of the four-game set tonight. Yusei Kikuchi will be on the mound for Seattle.