(East Rutherford, NJ) -- Nick Mullens threw for 343 yards and a touchdown in place of the injured Jimmy Garoppolo, as the 49ers crushed the Giants 36-9 at the Meadowlands. Jerick McKinnon, rookie wide receiver Brandon Aiyuk and Jeff Wilson all had rushing touchdowns for San Francisco, which moved to 2-and-1 with its second straight win. The Niners host the Eagles in Week Four.